Netrin: from guiding axons to clinical trials

Participants :

Greg Bashaw, Hua Linda Cai, Alain Chédotal (organiser), Christel Depienne, Mary Hynes, Marko Hyytiäinen, Marie Melissa Jasmin, Artur Kania, Manuel Koch, Fabrice Lavial, Patrick Mehlen (organiser), Philippe Monnier, Kathryn Moore, Romain Parent, Jonathan Raper, Anna Maria Rita Redavid, Sergi Roig Puiggros, Mike Sapieha, Elena Seiradake, Marc Tessier-Lavigne, Keqiang Ye


Netrin: from guiding axons to clinical trials
Organisers: Patrick Mehlen (Centre de Recherche en Cancérologie de Lyon, Lyon, France and Alain Chédotal (Institut de la Vision, Paris, France)
24 – 29 July, 2017

Key words: netrin; cancer; embryonic development; axon guidance; brain; neurodegenerative disease; diabete; macrophage

Participants and presentations:

Greg BASHAW University of Pennsylvania Conserved mechanisms of axon guidance receptor sorting and signaling at the midline in fly and mouse
Hua Linda CAI University of California Netrin-1 in cardiovascular protection
Alain CHÉDOTAL Institut de la Vision Role of Netrin1 and its receptors in the development and evolution of commissural systems
Christel DEPIENNE Hôpitaux universitaires de Strasbourg Dominant Mutations in DCC cause agenesis of the corpus callosum in humans
Mary HYNES Stanford University Netrin-mediated guidance of dopaminergic axons ; and Novel RNA processing
Marko HYYTIÄINEN University of Helsinki Netrin-1 in glioblastoma invasive processes
Marie Melissa JASMIN Centre de recherche en cancérologie de Lyon (CRCL) Netrin-1 and Parkinson’s disease
Artur KANIA Institut de Recherches Cliniques de Montréal (IRCM) Ephrin potentiates Netrin signalling
Manuel KOCH Institute for Dental Research and Oral Muskuloskeletal Biology/ Biochemistry II Structural insights into netrin-1 and -4 functions
Fabrice LAVIAL Cancer research center of Lyon Control of self-renewal and lineage commitment by bifunctional signalling in stem cells
Patrick MEHLEN Centre Léon Bérard Netrin-1 as a survival factor: therapeutic application
Philippe MONNIER Krembil Research Institute/ University Health Network Neogenin is involved in multiple CNS conditions
Kathryn MOORE New York University School of Medicine Role of netrin-1 in chronic inflammatory diseases
Romain PARENT Centre de recherche en cancérologie de Lyon (CRCL) Netrin-1, netrin-1 receptors and Hepatitis virus
Jonathan RAPER University of Pennsylvania Axon guidance in the olfactory system
Anna Maria Rita REDAVID CRCL Netrin-1 and Tumor Immunosurveillance
Sergi ROIG PUIGGROS Institut de la Vision The role of Netrin-1 in precerebelar neurons migration
Mike (Przemyslaw) SAPIEHA University of Montreal Netrin in Retinal Vascular Disease
Elena SEIRADAKE University of Oxford Unc5 and FLRT complexes
Marc TESSIER-LAVIGNE Stanford University Function and mechanism of Netrins in axon guidance
Keqiang YE Emory University Netrin Deprivation Triggers Delta-secretase Activation in Neurodegenerative Diseases

 Read the review in French

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